USING PREVIOUSLY GENOTYPED CONTROLS IN GENOME-WIDE ASSOCIATION STUDIES (GWAS): APPLICATION TO THE STROKE GENETICS NETWORK (SIGN)

Using previously genotyped controls in genome-wide association studies (GWAS): application to the Stroke Genetics Network (SiGN)

Genome-wide association studies (GWAS) are widely applied to identify susceptibility loci for a variety of diseases using genotyping arrays that interrogate known polymorphisms throughout the genome.A particular strength of GWAS is that it is unbiased with respect to specific genomic elements (e.g., coding or regulatory regions of genes), and it ha

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Machine learning-based mathematical equations for dengue positivity detection using elementary laboratory parameters

Objectives: Dengue is a common and important arboviral infection transmitted by the domestic Aedes aegypti mosquito.Dengue has managed to create a huge burden on public health globally.Severe dengue may prove to be fatal.Hence, early recognition of severe cases is essential for proper management.However, the traditional methods of dengue diagnosis

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